Achille Pich
e-mail: achille.pich AT unito.it
affiliation: Università di Torino
research area(s): Cancer Biology, Experimental Medicine
Course:
Biomedical Sciences and Human Oncology
University/Istitution: Università di Torino
University/Istitution: Università di Torino
NAME: Achille
SURNAME: PICH
PROFESSION: MD, Associate Professor of Pathology
DATE & PLACE OF BIRTH: June 16, 1949; Nole (Torino), Italy
CITIZENSHIP: Italian
FORMAL EDUCATION:
1963-1968 Classic Lyceum
1968-1974 University of Torino Medical School, Italy: M.D.(summa cum laude)
ACADEMIC TRAINING
1968 - 1970 Extern, Department of Anatomy, University of Torino Medical School
1971 - 1974 Extern, Department of Pathology, University of Torino Medical School
1974 - 1977 University Researcher, Department of Pathology, University of Torino Medical School
1977 - 1985 Assistant Professor, Department of Pathology, University of Torino Medical School
1986 - present Associate Professor, Department of Pathology, University of Torino Medical School
BOARD CERTIFICATION:
1974 Medical License, Italy (summa cum laude)
1982 Board in General Surgery, Italy (summa cum laude)
1986 Board in Laboratory Medicine, Italy (summa cum laude)
CLINICAL PATHOLOGY ACTIVITY:
1974-present General Clinical Pathology Physician, University of Torino Medical School and “San Giovanni Battista Hospital”, Torino, Italy
Specialty fields: Hematopathology (Bone marrow)
MEMBERSHIP
SIAPEC since 1995.
IAP since 1988.
ISPO (International Society for Preventive Oncology) since 1993.
EBMWG (European Bone Marrow Working Group) since 2007.
REVIEWER
1) British Journal of Cancer
2) Clinical Cancer Research
3) Histology and Histopathology
4) International Journal of Cancer
5) Journal of Clinical Pathology
6) Journal of Histochemistry and Cytochemistry,
7) Micron
8) Pathology Research and Practice
9) Virchows Archiv
10) European Journal of Histochemistry
11) British Journal of Haematology
12) Asian Journal of Andrology
13) International Journal of Experimental Pathology
14) Current Urology
15) European Journal of Haematology
16) Clinical and Experimental Medicine
SURNAME: PICH
PROFESSION: MD, Associate Professor of Pathology
DATE & PLACE OF BIRTH: June 16, 1949; Nole (Torino), Italy
CITIZENSHIP: Italian
FORMAL EDUCATION:
1963-1968 Classic Lyceum
1968-1974 University of Torino Medical School, Italy: M.D.(summa cum laude)
ACADEMIC TRAINING
1968 - 1970 Extern, Department of Anatomy, University of Torino Medical School
1971 - 1974 Extern, Department of Pathology, University of Torino Medical School
1974 - 1977 University Researcher, Department of Pathology, University of Torino Medical School
1977 - 1985 Assistant Professor, Department of Pathology, University of Torino Medical School
1986 - present Associate Professor, Department of Pathology, University of Torino Medical School
BOARD CERTIFICATION:
1974 Medical License, Italy (summa cum laude)
1982 Board in General Surgery, Italy (summa cum laude)
1986 Board in Laboratory Medicine, Italy (summa cum laude)
CLINICAL PATHOLOGY ACTIVITY:
1974-present General Clinical Pathology Physician, University of Torino Medical School and “San Giovanni Battista Hospital”, Torino, Italy
Specialty fields: Hematopathology (Bone marrow)
MEMBERSHIP
SIAPEC since 1995.
IAP since 1988.
ISPO (International Society for Preventive Oncology) since 1993.
EBMWG (European Bone Marrow Working Group) since 2007.
REVIEWER
1) British Journal of Cancer
2) Clinical Cancer Research
3) Histology and Histopathology
4) International Journal of Cancer
5) Journal of Clinical Pathology
6) Journal of Histochemistry and Cytochemistry,
7) Micron
8) Pathology Research and Practice
9) Virchows Archiv
10) European Journal of Histochemistry
11) British Journal of Haematology
12) Asian Journal of Andrology
13) International Journal of Experimental Pathology
14) Current Urology
15) European Journal of Haematology
16) Clinical and Experimental Medicine
SCIENTIFIC ACTIVITY
Research on tumor cell proliferative activity, oncogene expression, hematopathology (especially bone marrow pathology), mammary (especially male breast) and cervical pathology, experimental pathology and angiogenesis.
Member of the European Bone Marrow Working Group.
Main research topics (and major scientific achievements): Identification and localisation of milk proteins in dysplastic and neoplastic mammary lesions. Angiogenic activity of hyperplastic and neoplastic lymphoid tissue. Role of HPV in the evolution of condilomata and dysplasias of the uterine cervix. Prognostic value of the proliferative activity in pharyngeal, bladder, prostate and male breast carcinomas, multiple myeloma and thymoma. Prognostic and predictive value of AgNORs in acute myelogenous leukaemia (Pich et al. J Clin Oncol 16,1512-8,1998, selected for the 2000 Year Book of Pathology) and adult acute lymphoblastic leukemia. Prognostic value of p53 expression in thymoma, lymphoma and male breast carcinoma (Pich et al. J Clin Oncol 18,2948-56,2000, selected as "Article of the day" October 12, 2000 by AMEDEO, The Medical Literature Guide). Prognostic value of the expression of WT1 gene transcript in adult lymphoblastic leukemia. JAK2V617F mutation in RARS-T and chronic myelomonocytic leukaemia.
Author and co-author of 174 scientific publications.
Research on tumor cell proliferative activity, oncogene expression, hematopathology (especially bone marrow pathology), mammary (especially male breast) and cervical pathology, experimental pathology and angiogenesis.
Member of the European Bone Marrow Working Group.
Main research topics (and major scientific achievements): Identification and localisation of milk proteins in dysplastic and neoplastic mammary lesions. Angiogenic activity of hyperplastic and neoplastic lymphoid tissue. Role of HPV in the evolution of condilomata and dysplasias of the uterine cervix. Prognostic value of the proliferative activity in pharyngeal, bladder, prostate and male breast carcinomas, multiple myeloma and thymoma. Prognostic and predictive value of AgNORs in acute myelogenous leukaemia (Pich et al. J Clin Oncol 16,1512-8,1998, selected for the 2000 Year Book of Pathology) and adult acute lymphoblastic leukemia. Prognostic value of p53 expression in thymoma, lymphoma and male breast carcinoma (Pich et al. J Clin Oncol 18,2948-56,2000, selected as "Article of the day" October 12, 2000 by AMEDEO, The Medical Literature Guide). Prognostic value of the expression of WT1 gene transcript in adult lymphoblastic leukemia. JAK2V617F mutation in RARS-T and chronic myelomonocytic leukaemia.
Author and co-author of 174 scientific publications.
1. Pich A, Chiusa L, Margaria E. Prognostic relevance of AgNORs in tumor pathology.
Micron 31, 133-141, 2000.
2. Pich A, Margaria E, Chiusa L. Oncogenes and male breast carcinoma: c-erbB-2 and p53 coexpression predicts a poor survival.
J Clin Oncol 18, 2948-2956, 2000.
3. Margaria E, Chiusa L, Ferrari L, Dal Canton O, Pich A. Therapy and survival in male breast carcinoma: a retrospective analysis of 50 cases.
Oncol Rep 7, 1035-1039, 2000.
4. Chiusa L, Margaria E, Pich A. Nuclear morphometry in male breast carcinoma: association with cell proliferative activity, oncogene expression, DNA content and prognosis.
Int J Cancer 89, 494-499, 2000.
5. Pich A, Chiusa L, Formiconi A, Galliano D, Bortolin P, Navone R. Biologic differences between noninvasive papillary urothelial neoplasms of low malignant potential and low-grade (grade 1) papillary carcinomas of the bladder.
Am J Surg Pathol 25, 1528-1533, 2001.
6. Pich A, Chiusa L, Formiconi A, Galliano D, Bortolin P, Comino A, Navone R. Proliferative activity is the most significant predictor of recurrence in non-invasive papillary urothelial neoplasms of low malignant potential and grade 1 papillary carcinomas of the bladder.
Cancer 95, 784-790, 2002.
7. Pich A, Margaria E, Chiusa L, Bortolin P, Palestro G. Relationship between AgNORs, MIB-1 and oncogene expression in male breast carcinoma and papillary superficial bladder neoplasm.
Oncol Rep 10, 1329-1336, 2003.
8. Pich A, Chiusa L, Ceretto C, Fornari A, Audisio E, Marmont F, Navone R. Prognostic value of the rapidity of bone marrow blast cell proliferation in acute lymphoblastic leukemia.
Leukemia 18, 172-174, 2004.
9. Pich A, Chiusa L. Navone R. Prognostic relevance of cell proliferation in head and neck tumors.
Ann Oncol 15, 1319-1329, 2004.
10. Pich A, Galliano D. Pure (non-papillary) serous cystadenoma of the epididymis: a histologic and immunohistochemical study.
Pathol Res Pract 201, 65-69, 2005.
11. Chiusa L, Francia di Celle P, Campisi P, Ceretto C, Marmont F, Pich A. Prognostic value of quantitative analysis of WT1 gene transcripts in adult acute lymphoblastic leukemia.
Haematologica 91, 270-271, 2006.
12. Pich A, Fraire F, Fornari A, Davico Bonino L, Godio L, Bortolin P, Chiusa L, Palestro G. Intrasinusoidal bone marrow infiltration and splenic marginal zone lymphoma: a quantitative study.
Eur J Haematol 76, 392.398, 2006.
13. Pich A, Fraire F, Fornari A, Davico Bonino L, Godio L, Bortolin P, Chiusa L, Palestro G. Authors response to Tripodo et al. “Reply to Pich et al.: Intrasinusoidal bone marrow infiltration and splenic marginal zone lymphoma: a quantitative study.”
Eur J Haematol 77, 361, 2006.
14. Navone R, Burlo P, Pich A, Pentenero M, Broccoletti R, Marsico A, Gandolfo S. The impact of liquid-based oral cytology on the diagnosis of oral squamous displasia and carcinoma.
Cytopathology 18, 356-360, 2007.
15. Pich A, Riera L, Sismondi F, Godio L, Davico Bonino L, Marmont F, Francia di Celle P. JAK2V617F activating mutation is associated with the myeloproliferative type of chronic myelomonocytic leukaemia.
J Clin Pathol 62, 798-801, 2009.
16. Pich A. Godio L. Refractory anaemia with ring sideroblasts associated with marked thrombocytosis (RARS-T) and JAK2V617F mutation transformed to acute myeloid leukaemia with chromosomal evolution including monosomy 7.
Leukemia Res 34, e69-70, 2010.
17. Barreca A, Fornari A, Bonello L, Tondat F, Chiusa L, Lista P, Pich A. KIT and PDGFRA mutations and PDGFRA immunostaining in gastrointestinal stromal tumors.
Mol Med Rep 4: 3-8, 2011
18. Riera L, Lasorsa E, Bonello L, Sismondi F, Tondat F, Francia di Celle P, Chiarle R, Godio L, Pich A, Facchetti F, Ponzoni M, Marmont F, Zanon C, Bardelli A, Inghirami G. Description of a novel Janus kinase 3 P132A mutation in acute megakaryoblastic leukemia and demonstration of previously reported Janus kinase 3 mutations in normal subjects. Leukemia Lymphoma 52: 1–11, 2011
Micron 31, 133-141, 2000.
2. Pich A, Margaria E, Chiusa L. Oncogenes and male breast carcinoma: c-erbB-2 and p53 coexpression predicts a poor survival.
J Clin Oncol 18, 2948-2956, 2000.
3. Margaria E, Chiusa L, Ferrari L, Dal Canton O, Pich A. Therapy and survival in male breast carcinoma: a retrospective analysis of 50 cases.
Oncol Rep 7, 1035-1039, 2000.
4. Chiusa L, Margaria E, Pich A. Nuclear morphometry in male breast carcinoma: association with cell proliferative activity, oncogene expression, DNA content and prognosis.
Int J Cancer 89, 494-499, 2000.
5. Pich A, Chiusa L, Formiconi A, Galliano D, Bortolin P, Navone R. Biologic differences between noninvasive papillary urothelial neoplasms of low malignant potential and low-grade (grade 1) papillary carcinomas of the bladder.
Am J Surg Pathol 25, 1528-1533, 2001.
6. Pich A, Chiusa L, Formiconi A, Galliano D, Bortolin P, Comino A, Navone R. Proliferative activity is the most significant predictor of recurrence in non-invasive papillary urothelial neoplasms of low malignant potential and grade 1 papillary carcinomas of the bladder.
Cancer 95, 784-790, 2002.
7. Pich A, Margaria E, Chiusa L, Bortolin P, Palestro G. Relationship between AgNORs, MIB-1 and oncogene expression in male breast carcinoma and papillary superficial bladder neoplasm.
Oncol Rep 10, 1329-1336, 2003.
8. Pich A, Chiusa L, Ceretto C, Fornari A, Audisio E, Marmont F, Navone R. Prognostic value of the rapidity of bone marrow blast cell proliferation in acute lymphoblastic leukemia.
Leukemia 18, 172-174, 2004.
9. Pich A, Chiusa L. Navone R. Prognostic relevance of cell proliferation in head and neck tumors.
Ann Oncol 15, 1319-1329, 2004.
10. Pich A, Galliano D. Pure (non-papillary) serous cystadenoma of the epididymis: a histologic and immunohistochemical study.
Pathol Res Pract 201, 65-69, 2005.
11. Chiusa L, Francia di Celle P, Campisi P, Ceretto C, Marmont F, Pich A. Prognostic value of quantitative analysis of WT1 gene transcripts in adult acute lymphoblastic leukemia.
Haematologica 91, 270-271, 2006.
12. Pich A, Fraire F, Fornari A, Davico Bonino L, Godio L, Bortolin P, Chiusa L, Palestro G. Intrasinusoidal bone marrow infiltration and splenic marginal zone lymphoma: a quantitative study.
Eur J Haematol 76, 392.398, 2006.
13. Pich A, Fraire F, Fornari A, Davico Bonino L, Godio L, Bortolin P, Chiusa L, Palestro G. Authors response to Tripodo et al. “Reply to Pich et al.: Intrasinusoidal bone marrow infiltration and splenic marginal zone lymphoma: a quantitative study.”
Eur J Haematol 77, 361, 2006.
14. Navone R, Burlo P, Pich A, Pentenero M, Broccoletti R, Marsico A, Gandolfo S. The impact of liquid-based oral cytology on the diagnosis of oral squamous displasia and carcinoma.
Cytopathology 18, 356-360, 2007.
15. Pich A, Riera L, Sismondi F, Godio L, Davico Bonino L, Marmont F, Francia di Celle P. JAK2V617F activating mutation is associated with the myeloproliferative type of chronic myelomonocytic leukaemia.
J Clin Pathol 62, 798-801, 2009.
16. Pich A. Godio L. Refractory anaemia with ring sideroblasts associated with marked thrombocytosis (RARS-T) and JAK2V617F mutation transformed to acute myeloid leukaemia with chromosomal evolution including monosomy 7.
Leukemia Res 34, e69-70, 2010.
17. Barreca A, Fornari A, Bonello L, Tondat F, Chiusa L, Lista P, Pich A. KIT and PDGFRA mutations and PDGFRA immunostaining in gastrointestinal stromal tumors.
Mol Med Rep 4: 3-8, 2011
18. Riera L, Lasorsa E, Bonello L, Sismondi F, Tondat F, Francia di Celle P, Chiarle R, Godio L, Pich A, Facchetti F, Ponzoni M, Marmont F, Zanon C, Bardelli A, Inghirami G. Description of a novel Janus kinase 3 P132A mutation in acute megakaryoblastic leukemia and demonstration of previously reported Janus kinase 3 mutations in normal subjects. Leukemia Lymphoma 52: 1–11, 2011
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